Lupus is a chronic autoimmune condition where the immune system mistakenly targets healthy tissues, leading to inflammation and damage in various body parts, such as the skin, joints, and organs. Symptoms are diverse, ranging from fatigue and joint pain to rashes and fevers, often flaring up intermittently. Complications can be serious, particularly if the condition is not treated. The exact causes of lupus are unclear, though genetic, environmental, and hormonal factors are likely. Diagnosing lupus typically requires a comprehensive evaluation, including medical history, physical examination, and blood tests. Treatment aims to control symptoms and may involve anti-inflammatory medications, immunosuppressants, and biologics. Regular medical follow-up and lifestyle modifications are essential to manage the disease effectively, prevent flare-ups and maintain a good quality of life.